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OxyContin® (oxycodone HCl) is indicated for the management of pain severe enough to require daily, around-the-clock, long-term opioid treatment and for which alternative treatment options are inadequate.

How It's Used

Generally, OxyContin is prescribed to be taken twice a day, a benefit over other pain-relieving medications that have to be taken several times a day. OxyContin is available in tablet form in seven dosage levels from 10 to 80 milligrams.

It is usually prescribed to help patients with chronic pain, such as back and neck pain. It may also be prescribed to cancer patients to help decrease pain and improve function

How It's Abused

People who misuse OxyContin use the medicine in amounts or ways that are not prescribed or intended. They can either crush the tablet and ingest or snort it, or they dilute it in water and inject it. Crushing or diluting the tablet disarms the timed-release action of the medication, but crushing OxyContin in this way can give the user a potentially fatal dose.2

In 2010, the FDA approved a new formulation of OxyContin to prevent such tampering. The drugmaker, Purdue Pharma LP, made changes so that breaking up the tablet does not immediately release oxycodone. Also, if someone attempts to dissolve these new tablets for syringe injection, the liquid becomes gummy.

Despite these measures, the FDA continues to admit that abuse and misuse of OxyContin remain possible. Further, there is an increase in OxyContin abusers who are turning to heroin because it is a significantly lower-cost opioid.

According to a 2013 study, nearly 80% of American heroin users reported misusing prescription opioids like OxyContin and Vicodin before they were introduced to the illicit street drug.3

Some of the street names for OxyContin include Oxy, O.C., Cotton, kickers, Ox, OCs, beans, rushbo, Orange County, killer, and hillbilly heroin. It is frequently mispronounced and misspelled as "oxycotton."

If you or a loved one are struggling with substance use or addiction, contact the Substance Abuse and Mental Health Services Administration (SAMHSA) National Helpline at 1-800-662-4357 for information on support and treatment facilities in your area.

For more mental health resources, see our National Helpline Database.

Effects

Under the prescribed dosage, OxyContin is an effective pain reliever. When crushed and snorted or injected, the drug produces a quick and powerful "high" that some abusers compare to the feeling they get when doing heroin. The National Institute on Drug Abuse (NIDA) reports that in some areas of the country, OxyContin abuse rates are higher than heroin abuse.

OxyContin, like heroin and other opioids, is a central nervous system depressant. An overdose can cause respiratory failure and death.

Some symptoms of OxyContin overdose include:

Clouding of mental functions

Cold and clammy skin

Coma

Confusion

Dizziness

Loss of consciousness

Nausea

Reduced vision

Seizures

Slow breathing (respiratory depression)

Small pupils

Tiredness

Vomiting

Weakness

In Case of Overdose

If you believe someone has taken an overdose of OxyContin, call 9-1-1 immediately. Narcan (naloxone hydrochloride) is an emergency medication designed to counteract an opioid overdose. First-responders can use it to revive someone if they can reach them soon enough.

If medical attention is received promptly, there may be few long-term consequences of an overdose. When treatment is delayed, an overdose of OxyContin can be fatal or result in permanent brain damage.